Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation

The seven-transmembrane receptor Smoothened (Smo) activates all Hedgehog (Hh) signaling by translocation into the primary cilia (PC), but how this is regulated is not well understood. Here we show that Pitchfork (Pifo) and the G protein-coupled receptor associated sorting protein 2 (Gprasp2) are ess...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jung, Bomi, Padula, Daniela, Burtscher, Ingo, Landerer, Cedric, Lutter, Dominik, Theis, Fabian, Messias, Ana C., Geerlof, Arie, Sattler, Michael, Kremmer, Elisabeth, Boldt, Karsten, Ueffing, Marius, Lickert, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763541/
https://ncbi.nlm.nih.gov/pubmed/26901434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149477
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados