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Dithiothreitol (DTT) Acts as a Specific, UV-inducible Cross-linker in Elucidation of Protein–RNA Interactions

Protein–RNA cross-linking by UV irradiation at 254 nm wavelength has been established as an unbiased method to identify proteins in direct contact with RNA, and has been successfully applied to investigate the spatial arrangement of protein and RNA in large macromolecular assemblies, e.g. ribonucleo...

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Библиографические подробности
Опубликовано в: :Mol Cell Proteomics
Главные авторы: Zaman, Uzma, Richter, Florian M., Hofele, Romina, Kramer, Katharina, Sachsenberg, Timo, Kohlbacher, Oliver, Lenz, Christof, Urlaub, Henning
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762631/
https://ncbi.nlm.nih.gov/pubmed/26450613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.052795
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