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Expressing Transgenes That Exceed the Packaging Capacity of Adeno-Associated Virus Capsids
Recombinant adeno-associated virus vectors (rAAV) are being explored as gene delivery vehicles for the treatment of various inherited and acquired disorders. rAAVs are attractive vectors for several reasons: wild-type AAVs are nonpathogenic, and rAAVs can trigger long-term transgene expression even...
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| Опубликовано в: : | Hum Gene Ther Methods |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Mary Ann Liebert, Inc.
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4761816/ https://ncbi.nlm.nih.gov/pubmed/26757051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2015.140 |
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