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DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids

Helicases not only catalyse the disruption of hydrogen bonding between complementary regions of nucleic acids, but also move along nucleic acid strands in a polar fashion. Here we show that the Rep52 and Rep40 proteins of adeno-associated virus type 2 (AAV-2) are required to translocate capsid-assoc...

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Detalhes bibliográficos
Main Authors: King, Jason A., Dubielzig, Ralf, Grimm, Dirk, Kleinschmidt, Jürgen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150213/
https://ncbi.nlm.nih.gov/pubmed/11406604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.3282
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