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DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids
Helicases not only catalyse the disruption of hydrogen bonding between complementary regions of nucleic acids, but also move along nucleic acid strands in a polar fashion. Here we show that the Rep52 and Rep40 proteins of adeno-associated virus type 2 (AAV-2) are required to translocate capsid-assoc...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150213/ https://ncbi.nlm.nih.gov/pubmed/11406604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.3282 |
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