Non-catalytic Roles For XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability

XPG is a structure-specific endonuclease required for nucleotide excision repair, and incision-defective Xpg mutations cause the skin cancer-prone syndrome xeroderma pigmentosum. Truncating mutations instead cause the neurodevelopmental progeroid disorder Cockayne syndrome, but little is known about...

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Publicado no:Mol Cell
Main Authors: Trego, Kelly S., Groesser, Torsten, Davalos, Albert R., Parplys, Ann C., Zhao, Weixing, Nelson, Michael R., Hlaing, Ayesu, Shih, Brian, Rydberg, Björn, Pluth, Janice M., Tsai, Miaw-Sheue, Hoeijmakers, Jan H.J., Sung, Patrick, Wiese, Claudia, Campisi, Judith, Cooper, Priscilla K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761302/
https://ncbi.nlm.nih.gov/pubmed/26833090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.12.026
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