Promotion of Homologous Recombination and Genomic Stability by RAD51AP1 via RAD51 Recombinase Enhancement

Homologous recombination (HR) repairs chromosome damage and is indispensable for tumor suppression in humans. RAD51 mediates the DNA strand pairing step in HR. RAD51AP1 (RAD51 Associated Protein 1) is a RAD51-interacting protein whose function has remained elusive. Knockdown of RAD51AP1 in human cel...

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Hauptverfasser: Wiese, Claudia, Dray, Eloïse, Groesser, Torsten, Filippo, Joseph San, Shi, Idina, Collins, David W., Tsai, Miaw-Sheue, Williams, Gareth, Rydberg, Bjorn, Sung, Patrick, Schild, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169287/
https://ncbi.nlm.nih.gov/pubmed/17996711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.08.027
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