Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1)

Homologous recombination is needed for meiotic chromosome segregation, genome maintenance, and tumor suppression. RAD51AP1 (RAD51 associated protein 1) has been shown to interact with and enhance the recombinase activity of RAD51. Accordingly, genetic ablation of RAD51AP1 leads to enhanced sensitivi...

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Autors principals: Dray, Eloïse, Dunlop, Myun Hwa, Kauppi, Liisa, Filippo, Joseph San, Wiese, Claudia, Tsai, Miaw-Sheue, Begovic, Sead, Schild, David, Jasin, Maria, Keeney, Scott, Sung, Patrick
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048120/
https://ncbi.nlm.nih.gov/pubmed/21307306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016454108
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