The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome

XPG is a structure-specific endonuclease required for nucleotide excision repair (NER). XPG incision defects result in the cancer-prone syndrome xeroderma pigmentosum, whereas truncating mutations of XPG cause the severe postnatal progeroid developmental disorder Cockayne syndrome. We show that XPG...

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Detaylı Bibliyografya
Asıl Yazarlar: Trego, Kelly S, Chernikova, Sophia B, Davalos, Albert R, Perry, J Jefferson P, Finger, L David, Ng, Cliff, Tsai, Miaw-Sheue, Yannone, Steven M, Tainer, John A, Campisi, Judith, Cooper, Priscilla K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2011
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154418/
https://ncbi.nlm.nih.gov/pubmed/21558802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.12.15878
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