The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome

XPG is a structure-specific endonuclease required for nucleotide excision repair (NER). XPG incision defects result in the cancer-prone syndrome xeroderma pigmentosum, whereas truncating mutations of XPG cause the severe postnatal progeroid developmental disorder Cockayne syndrome. We show that XPG...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Trego, Kelly S, Chernikova, Sophia B, Davalos, Albert R, Perry, J Jefferson P, Finger, L David, Ng, Cliff, Tsai, Miaw-Sheue, Yannone, Steven M, Tainer, John A, Campisi, Judith, Cooper, Priscilla K
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2011
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154418/
https://ncbi.nlm.nih.gov/pubmed/21558802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.12.15878
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