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WRN helicase expression in Werner syndrome cell lines

Mutations in the chromosome 8p WRN gene cause Werner syndrome (WRN), a human autosomal recessive disease that mimics premature aging and is associated with genetic instability and an increased risk of cancer. All of the WRN mutations identified in WRN patients are predicted to truncate the WRN prote...

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Autores principales: Moser, Michael J., Kamath-Loeb, Ashwini S., Jacob, Jessica E., Bennett, Samuel E., Oshima, Junko, Monnat, Raymond J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC102521/
https://ncbi.nlm.nih.gov/pubmed/10606667
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