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Physiologically Based Modelling of Darunavir/Ritonavir Pharmacokinetics During Pregnancy
Pregnant women are usually excluded from clinical trials. Physiologically based pharmacokinetic (PBPK) modelling may provide a method to predict pharmacokinetics in pregnant women, without the need to perform extensive in vivo clinical trials. Here, we used mechanistic modelling to delineate the pot...
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| Gepubliceerd in: | Clin Pharmacokinet |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer International Publishing
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4761019/ https://ncbi.nlm.nih.gov/pubmed/26369773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-015-0325-8 |
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