Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment

In a positron-emission tomography (PET) study with the β-amyloid (Aβ) tracer [(18)F]-florbetaben, we previously showed that Aβ deposition in transgenic mice expressing Swedish mutant APP (APP-Swe) mice can be tracked in vivo. γ-Secretase modulators (GSMs) are promising therapeutic agents by reducing...

詳細記述

保存先:
書誌詳細
出版年:Mol Psychiatry
主要な著者: Brendel, M, Jaworska, A, Herms, J, Trambauer, J, Rötzer, C, Gildehaus, F-J, Carlsen, J, Cumming, P, Bylund, J, Luebbers, T, Bartenstein, P, Steiner, H, Haass, C, Baumann, K, Rominger, A
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759098/
https://ncbi.nlm.nih.gov/pubmed/26055427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.74
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料