Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice

Preclinical PET studies of β-amyloid (Aβ) accumulation are of growing importance, but comparisons between research sites require standardized and optimized methods for quantitation. Therefore, we aimed to evaluate systematically the (1) impact of an automated algorithm for spatial brain normalizatio...

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Bibliografske podrobnosti
izdano v:Front Neurosci
Main Authors: Overhoff, Felix, Brendel, Matthias, Jaworska, Anna, Korzhova, Viktoria, Delker, Andreas, Probst, Federico, Focke, Carola, Gildehaus, Franz-Josef, Carlsen, Janette, Baumann, Karlheinz, Haass, Christian, Bartenstein, Peter, Herms, Jochen, Rominger, Axel
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770021/
https://ncbi.nlm.nih.gov/pubmed/26973442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00045
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