Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice

Preclinical PET studies of β-amyloid (Aβ) accumulation are of growing importance, but comparisons between research sites require standardized and optimized methods for quantitation. Therefore, we aimed to evaluate systematically the (1) impact of an automated algorithm for spatial brain normalizatio...

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Pubblicato in:Front Neurosci
Autori principali: Overhoff, Felix, Brendel, Matthias, Jaworska, Anna, Korzhova, Viktoria, Delker, Andreas, Probst, Federico, Focke, Carola, Gildehaus, Franz-Josef, Carlsen, Janette, Baumann, Karlheinz, Haass, Christian, Bartenstein, Peter, Herms, Jochen, Rominger, Axel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770021/
https://ncbi.nlm.nih.gov/pubmed/26973442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00045
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