Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice

Preclinical PET studies of β-amyloid (Aβ) accumulation are of growing importance, but comparisons between research sites require standardized and optimized methods for quantitation. Therefore, we aimed to evaluate systematically the (1) impact of an automated algorithm for spatial brain normalizatio...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Overhoff, Felix, Brendel, Matthias, Jaworska, Anna, Korzhova, Viktoria, Delker, Andreas, Probst, Federico, Focke, Carola, Gildehaus, Franz-Josef, Carlsen, Janette, Baumann, Karlheinz, Haass, Christian, Bartenstein, Peter, Herms, Jochen, Rominger, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770021/
https://ncbi.nlm.nih.gov/pubmed/26973442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00045
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