Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study

BACKGROUND: Causal associations between microglia activation and β-amyloid (Aβ) accumulation during the progression of Alzheimer’s disease (AD) remain a matter of controversy. Therefore, we used longitudinal dual tracer in vivo small animal positron emission tomography (μPET) imaging to resolve the...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Blume, Tanja, Focke, Carola, Peters, Finn, Deussing, Maximilian, Albert, Nathalie L., Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Ozmen, Laurence, Baumann, Karlheinz, Bartenstein, Peter, Rominger, Axel, Herms, Jochen, Brendel, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220478/
https://ncbi.nlm.nih.gov/pubmed/30400912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1347-6
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