Caricamento...
Early phase clinical trials—are dose expansion cohorts needed?
Dose-expansion cohorts (DECs) enable investigators to identify potentially effective drugs, for specific patient populations, in a single trial by assessing antitumour activity as early as possible. We discuss how the objectives, design and interpretation of DEC have evolved, and how DECs are changi...
Salvato in:
| Pubblicato in: | Nat Rev Clin Oncol |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4758199/ https://ncbi.nlm.nih.gov/pubmed/26441082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2015.174 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|