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Structural requirements for protein-catalyzed annealing of U4 and U6 RNAs during di-snRNP assembly
Base-pairing of U4 and U6 snRNAs during di-snRNP assembly requires large-scale remodeling of RNA structure that is chaperoned by the U6 snRNP protein Prp24. We investigated the mechanism of U4/U6 annealing in vitro using an assay that enables visualization of ribonucleoprotein complexes and faithful...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4756825/ https://ncbi.nlm.nih.gov/pubmed/26673715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1374 |
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