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A Common Anesthetic Binding Site for Inhibition of Pentameric Ligand-gated Ion Channels

BACKGROUND: Identifying functionally relevant anesthetic binding sites in pentameric ligand-gated ion channels (pLGICs) is an important step toward understanding molecular mechanisms underlying anesthetic action. The anesthetic propofol is known to inhibit cation-conducting pLGICs, including a proka...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Anesthesiology
Prif Awduron: Kinde, Monica N., Bu, Weiming, Chen, Qiang, Xu, Yan, Eckenhoff, Roderic G., Tang, Pei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755840/
https://ncbi.nlm.nih.gov/pubmed/26756520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001005
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