A carregar...

Structural Basis of Alcohol Inhibition of the Pentameric Ligand-gated Ion Channel ELIC

The structural basis for alcohol modulation of neuronal pentameric ligand-gated ion channels (pLGICs) remains elusive. We determined an inhibitory mechanism of alcohol on the pLGIC Erwinia chrysanthemi (ELIC) through direct binding to the pore. X-ray structures of ELIC co-crystallized with 2-bromoet...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Structure
Main Authors: Chen, Qiang, Wells, Marta M., Tillman, Tommy S., Kinde, Monica N., Cohen, Aina, Xu, Yan, Tang, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214846/
https://ncbi.nlm.nih.gov/pubmed/27916519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.11.007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!