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A Common Anesthetic Binding Site for Inhibition of Pentameric Ligand-gated Ion Channels
BACKGROUND: Identifying functionally relevant anesthetic binding sites in pentameric ligand-gated ion channels (pLGICs) is an important step toward understanding molecular mechanisms underlying anesthetic action. The anesthetic propofol is known to inhibit cation-conducting pLGICs, including a proka...
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| Publicado no: | Anesthesiology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755840/ https://ncbi.nlm.nih.gov/pubmed/26756520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001005 |
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