Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial Biosynthesis

Plant‐derived diterpenoids serve as important pharmaceuticals, food additives, and fragrances, yet their low natural abundance and high structural complexity limits their broader industrial utilization. By mimicking the modularity of diterpene biosynthesis in plants, we constructed 51 functional com...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Andersen‐Ranberg, Johan, Kongstad, Kenneth Thermann, Nielsen, Morten Thrane, Jensen, Niels Bjerg, Pateraki, Irini, Bach, Søren Spanner, Hamberger, Britta, Zerbe, Philipp, Staerk, Dan, Bohlmann, Jörg, Møller, Birger Lindberg, Hamberger, Björn
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755150/
https://ncbi.nlm.nih.gov/pubmed/26749264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201510650
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