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Engineering of CYP76AH15 can improve activity and specificity towards forskolin biosynthesis in yeast
BACKGROUND: Forskolin is a high-value diterpenoid produced exclusively by the Lamiaceae plant Coleus forskohlii. Today forskolin is used pharmaceutically for its adenyl-cyclase activating properties. The limited availability of pure forskolin is currently hindering its full utilization, thus a new...
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| Publicado no: | Microb Cell Fact |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6240942/ https://ncbi.nlm.nih.gov/pubmed/30453976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-1027-3 |
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