Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial Biosynthesis

Plant‐derived diterpenoids serve as important pharmaceuticals, food additives, and fragrances, yet their low natural abundance and high structural complexity limits their broader industrial utilization. By mimicking the modularity of diterpene biosynthesis in plants, we constructed 51 functional com...

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Bibliographic Details
Published in:Angew Chem Int Ed Engl
Main Authors: Andersen‐Ranberg, Johan, Kongstad, Kenneth Thermann, Nielsen, Morten Thrane, Jensen, Niels Bjerg, Pateraki, Irini, Bach, Søren Spanner, Hamberger, Britta, Zerbe, Philipp, Staerk, Dan, Bohlmann, Jörg, Møller, Birger Lindberg, Hamberger, Björn
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755150/
https://ncbi.nlm.nih.gov/pubmed/26749264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201510650
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