Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial Biosynthesis

Plant‐derived diterpenoids serve as important pharmaceuticals, food additives, and fragrances, yet their low natural abundance and high structural complexity limits their broader industrial utilization. By mimicking the modularity of diterpene biosynthesis in plants, we constructed 51 functional com...

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發表在:Angew Chem Int Ed Engl
Main Authors: Andersen‐Ranberg, Johan, Kongstad, Kenneth Thermann, Nielsen, Morten Thrane, Jensen, Niels Bjerg, Pateraki, Irini, Bach, Søren Spanner, Hamberger, Britta, Zerbe, Philipp, Staerk, Dan, Bohlmann, Jörg, Møller, Birger Lindberg, Hamberger, Björn
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Communications
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755150/
https://ncbi.nlm.nih.gov/pubmed/26749264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201510650
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