Antimitogenic effect of bitter taste receptor agonists on airway smooth muscle cells

Airway remodeling is a hallmark feature of asthma and chronic obstructive pulmonary disease. Clinical studies and animal models have demonstrated increased airway smooth muscle (ASM) mass, and ASM thickness is correlated with severity of the disease. Current medications control inflammation and reve...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Sharma, Pawan, Panebra, Alfredo, Pera, Tonio, Tiegs, Brian C., Hershfeld, Alena, Kenyon, Lawrence C., Deshpande, Deepak A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754903/
https://ncbi.nlm.nih.gov/pubmed/26684251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00373.2015
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