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Gene Therapy Restores Hair Cell Stereocilia Morphology in Inner Ears of Deaf Whirler Mice

Hereditary deafness is one of the most common disabilities affecting newborns. Many forms of hereditary deafness are caused by morphological defects of the stereocilia bundles on the apical surfaces of inner ear hair cells, which are responsible for sound detection. We explored the effectiveness of...

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Vydáno v:Mol Ther
Hlavní autoři: Chien, Wade W, Isgrig, Kevin, Roy, Soumen, Belyantseva, Inna A, Drummond, Meghan C, May, Lindsey A, Fitzgerald, Tracy S, Friedman, Thomas B, Cunningham, Lisa L
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754541/
https://ncbi.nlm.nih.gov/pubmed/26307667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.150
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