Gene Therapy Restores Hair Cell Stereocilia Morphology in Inner Ears of Deaf Whirler Mice

Hereditary deafness is one of the most common disabilities affecting newborns. Many forms of hereditary deafness are caused by morphological defects of the stereocilia bundles on the apical surfaces of inner ear hair cells, which are responsible for sound detection. We explored the effectiveness of...

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Pubblicato in:Mol Ther
Autori principali: Chien, Wade W, Isgrig, Kevin, Roy, Soumen, Belyantseva, Inna A, Drummond, Meghan C, May, Lindsey A, Fitzgerald, Tracy S, Friedman, Thomas B, Cunningham, Lisa L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754541/
https://ncbi.nlm.nih.gov/pubmed/26307667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.150
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