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Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle

Mutations of the gene encoding unconventional myosin XVa are associated with sensorineural deafness in humans (DFNB3) and shaker (Myo15(sh2)) mice. In deaf Myo15(sh2/sh2) mice, stereocilia are short, nearly equal in length, and lack myosin XVa immunoreactivity. We previously reported that myosin XVa...

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Detalhes bibliográficos
Main Authors: Belyantseva, Inna A., Boger, Erich T., Friedman, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC283528/
https://ncbi.nlm.nih.gov/pubmed/14610277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2334417100
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