Gene Therapy Restores Hair Cell Stereocilia Morphology in Inner Ears of Deaf Whirler Mice

Hereditary deafness is one of the most common disabilities affecting newborns. Many forms of hereditary deafness are caused by morphological defects of the stereocilia bundles on the apical surfaces of inner ear hair cells, which are responsible for sound detection. We explored the effectiveness of...

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Bibliografske podrobnosti
izdano v:Mol Ther
Main Authors: Chien, Wade W, Isgrig, Kevin, Roy, Soumen, Belyantseva, Inna A, Drummond, Meghan C, May, Lindsey A, Fitzgerald, Tracy S, Friedman, Thomas B, Cunningham, Lisa L
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754541/
https://ncbi.nlm.nih.gov/pubmed/26307667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.150
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