Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear

The maintenance of sensory hair cell stereocilia is critical for lifelong hearing; however, mechanisms of structural homeostasis remain poorly understood. Conflicting models propose that stereocilia F-actin cores are either continually renewed every 24–48 h via a treadmill or are stable, exceptional...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Drummond, Meghan C., Barzik, Melanie, Bird, Jonathan E., Zhang, Duan-Sun, Lechene, Claude P., Corey, David P., Cunningham, Lisa L., Friedman, Thomas B.
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411292/
https://ncbi.nlm.nih.gov/pubmed/25898120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7873
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items