Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

Genetic studies have revealed significant overlaps of risk genes among psychiatric disorders. However, it is not clear how different mutations of the same gene contribute to different disorders. We characterized two lines of mutant mice with Shank3 mutations linked to ASD and schizophrenia. We found...

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Опубликовано в: :Neuron
Главные авторы: Zhou, Yang, Kaiser, Tobias, Monteiro, Patrícia, Zhang, Xiangyu, Van der Goes, Marie. S., Wang, Dongqing, Barak, Boaz, Zeng, Menglong, Li, Chenchen, Lu, Congyi, Wells, Michael, Amaya, Aldo, Nguyen, Shannon, Lewis, Michael, Sanjana, Neville, Zhou, Yongdi, Zhang, Mingjie, Zhang, Feng, Fu, Zhanyan, Feng, Guoping
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754122/
https://ncbi.nlm.nih.gov/pubmed/26687841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.023
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