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Adult Restoration of Shank3 Expression Rescues Selective Autistic-Like Phenotypes

Because ASD is a neurodevelopmental disorder and patients typically display symptoms before the age of three(1), one of the key questions in autism research is whether the pathology is reversible in adults. Here we investigated the developmental requirement of Shank3, one of the most prominent monog...

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Detalles Bibliográficos
Publicado en:Nature
Main Authors: Mei, Yuan, Monteiro, Patricia, Zhou, Yang, Kim, Jin-Ah, Gao, Xian, Fu, Zhanyan, Feng, Guoping
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898763/
https://ncbi.nlm.nih.gov/pubmed/26886798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16971
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