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Chronic bryostatin-1 rescues autistic and cognitive phenotypes in the fragile X mice

Fragile X syndrome (FXS), an X-chromosome linked intellectual disability, is the leading monogenetic cause of autism spectrum disorder (ASD), a neurodevelopmental condition that currently has no specific drug treatment. Building upon the demonstrated therapeutic effects on spatial memory of bryostat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cogram, Patricia, Alkon, Daniel L., Crockford, David, Deacon, Robert M. J., Hurley, Michael J., Altimiras, Francisco, Sun, Miao-Kun, Tranfaglia, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581799/
https://ncbi.nlm.nih.gov/pubmed/33093534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74848-6
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