Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

Genetic studies have revealed significant overlaps of risk genes among psychiatric disorders. However, it is not clear how different mutations of the same gene contribute to different disorders. We characterized two lines of mutant mice with Shank3 mutations linked to ASD and schizophrenia. We found...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Neuron
المؤلفون الرئيسيون: Zhou, Yang, Kaiser, Tobias, Monteiro, Patrícia, Zhang, Xiangyu, Van der Goes, Marie. S., Wang, Dongqing, Barak, Boaz, Zeng, Menglong, Li, Chenchen, Lu, Congyi, Wells, Michael, Amaya, Aldo, Nguyen, Shannon, Lewis, Michael, Sanjana, Neville, Zhou, Yongdi, Zhang, Mingjie, Zhang, Feng, Fu, Zhanyan, Feng, Guoping
التنسيق: Artigo
اللغة:Inglês
منشور في: 2015
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754122/
https://ncbi.nlm.nih.gov/pubmed/26687841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.023
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