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Asymmetric Preorganization of Inverted Pair Residues in the Sodium-Calcium Exchanger

In analogy with many other proteins, Na(+)/Ca(2+) exchangers (NCX) adapt an inverted twofold symmetry of repeated structural elements, while exhibiting a functional asymmetry by stabilizing an outward-facing conformation. Here, structure-based mutant analyses of the Methanococcus jannaschii Na(+)/Ca...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Giladi, Moshe, Almagor, Lior, van Dijk, Liat, Hiller, Reuben, Man, Petr, Forest, Eric, Khananshvili, Daniel
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753433/
https://ncbi.nlm.nih.gov/pubmed/26876271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20753
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