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Structural Features of Ion Transport and Allosteric Regulation in Sodium-Calcium Exchanger (NCX) Proteins

Na(+)/Ca(2+) exchanger (NCX) proteins extrude Ca(2+) from the cell to maintain cellular homeostasis. Since NCX proteins contribute to numerous physiological and pathophysiological events, their pharmacological targeting has been desired for a long time. This intervention remains challenging owing to...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Giladi, Moshe, Tal, Inbal, Khananshvili, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746289/
https://ncbi.nlm.nih.gov/pubmed/26903880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00030
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