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Hydrogen-Deuterium Exchange Mass-Spectrometry of Secondary Active Transporters: From Structural Dynamics to Molecular Mechanisms

Membrane transporters allow the selective transport of otherwise poorly permeable solutes across the cell membrane and thus, play a key role in maintaining cellular homeostasis in all kingdoms of life. Importantly, these proteins also serve as important drug targets. Over the last decades, major pro...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Giladi, Moshe, Khananshvili, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042309/
https://ncbi.nlm.nih.gov/pubmed/32140107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00070
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