CD70 and IFN-1 selectively induce Eomesodermin or T-bet and synergize to promote CD8(+) T cell responses

CD70-mediated stimulation of CD27 is an important cofactor of CD4(+) T cell licensed dendritic cells. However, it is unclear how CD70-mediated stimulation of T cells is integrated with signals that emanate from Signal 3 pathways, such as type-1 interferon (IFN-1) and IL-12. We find that while stimul...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Eur J Immunol
Main Authors: Dong, Han, Franklin, Nathan A., Ritchea, Shane B., Yagita, Hideo, Glennie, Martin J., Bullock, Timothy N. J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752831/
https://ncbi.nlm.nih.gov/pubmed/26461455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201445291
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares