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CD70 and IFN-1 selectively induce Eomesodermin or T-bet and synergize to promote CD8(+) T cell responses
CD70-mediated stimulation of CD27 is an important cofactor of CD4(+) T cell licensed dendritic cells. However, it is unclear how CD70-mediated stimulation of T cells is integrated with signals that emanate from Signal 3 pathways, such as type-1 interferon (IFN-1) and IL-12. We find that while stimul...
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| Publicado no: | Eur J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752831/ https://ncbi.nlm.nih.gov/pubmed/26461455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201445291 |
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