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Osteoclast primed FoxP3(+) CD8 T-cells induce T-bet and Eomesodermin and IFN-γ to regulate bone resorption

Osteoimmunology arose from the recognition that cytokines produced by lymphocytes can affect bone homeostasis. We have previously shown that osteoclasts, cells that resorb bone, act as antigen-presenting cells. Cross-presentation of antigens by osteoclasts leads to expression of CD25 and FoxP3, mark...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Shashkova, Elena V., Trivedi, Jahnavi, Cline-Smith, Anna B., Ferris, Chloe, Buchwald, Zachary S., Gibbs, Jesse, Novack, Deborah, Aurora, Rajeev
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955741/
https://ncbi.nlm.nih.gov/pubmed/27324129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600253
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