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Osteoclast primed FoxP3(+) CD8 T-cells induce T-bet and Eomesodermin and IFN-γ to regulate bone resorption
Osteoimmunology arose from the recognition that cytokines produced by lymphocytes can affect bone homeostasis. We have previously shown that osteoclasts, cells that resorb bone, act as antigen-presenting cells. Cross-presentation of antigens by osteoclasts leads to expression of CD25 and FoxP3, mark...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955741/ https://ncbi.nlm.nih.gov/pubmed/27324129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600253 |
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