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Pulsed low-dose RANKL as a potential therapeutic for postmenopausal osteoporosis
A number of studies in model animal systems and in the clinic have established that RANKL promotes bone resorption. Paradoxically, we found that pulsing ovariectomized mice with low-dose RANKL suppressed bone resorption, decreased the levels of proinflammatory effector T cells and led to increased b...
Tallennettuna:
| Julkaisussa: | JCI Insight |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Clinical Investigation
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4996279/ https://ncbi.nlm.nih.gov/pubmed/27570837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88839 |
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