Ovariectomy Activates Chronic Low-Grade Inflammation Mediated by Memory T Cells, Which Promotes Osteoporosis in Mice

The loss of estrogen (E(2)) initiates a rapid phase of bone loss leading to osteoporosis in one-half of postmenopausal women, but the mechanism is not fully understood. Here, we show for the first time how loss of E(2) activates low-grade inflammation to promote the acute phase of bone catabolic act...

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Publicado en:J Bone Miner Res
Autores principales: Cline-Smith, Anna, Axelbaum, Ariel, Shashkova, Elena, Chakraborty, Mousumi, Sanford, Jessie, Panesar, Prabhjyot, Peterson, Macey, Cox, Linda, Baldan, Angel, Veis, Deborah, Aurora, Rajeev
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8061311/
https://ncbi.nlm.nih.gov/pubmed/31995253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3966
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