Alternative Pathway Inhibition by Exogenous Factor H Fails to Attenuate Inflammation and Vascular Leakage in Experimental Pneumococcal Sepsis in Mice

Streptococcus pneumoniae is a common cause of sepsis. Effective complement activation is an important component of host defence against invading pathogens, whilst excessive complement activation has been associated with endothelial dysfunction and organ damage. The alternative pathway amplification...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: van der Maten, Erika, van Selm, Saskia, Langereis, Jeroen D., Bootsma, Hester J., van Opzeeland, Fred J. H., de Groot, Ronald, de Jonge, Marien I., van der Flier, Michiel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752313/
https://ncbi.nlm.nih.gov/pubmed/26872035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149307
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