Limited Innovations After More Than 65 Years of Immunoglobulin Replacement Therapy: Potential of IgA- and IgM-Enriched Formulations to Prevent Bacterial Respiratory Tract Infections

Patients with primary immunoglobulin deficiency have lower immunoglobulin levels or decreased immunoglobulin function, which makes these patients more susceptible to bacterial infection. Most prevalent are the selective IgA deficiencies (~1:3,000), followed by common variable immune deficiency (~1:2...

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Publicat a:Front Immunol
Autors principals: Langereis, Jeroen D., van der Flier, Michiel, de Jonge, Marien I.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115500/
https://ncbi.nlm.nih.gov/pubmed/30190722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01925
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