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Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2)

Morphological disintegration of neurons is coupled invariably to neural death. In particular, disruption of outer segments of photoreceptor neurons triggers photoreceptor death regardless of the pathological stressors. We show that Ranbp2(−/−)::Tg-Ranbp2(CLDm) mice with mutations in SUMO-binding mot...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Cho, Kyoung-in, Haney, Victoria, Yoon, Dosuk, Hao, Yin, Ferreira, Paulo A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751886/
https://ncbi.nlm.nih.gov/pubmed/26632511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.11.037
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