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Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2)
Morphological disintegration of neurons is coupled invariably to neural death. In particular, disruption of outer segments of photoreceptor neurons triggers photoreceptor death regardless of the pathological stressors. We show that Ranbp2(−/−)::Tg-Ranbp2(CLDm) mice with mutations in SUMO-binding mot...
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| Publié dans: | FEBS Lett |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4751886/ https://ncbi.nlm.nih.gov/pubmed/26632511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.11.037 |
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