Inhibition of Monoacylglycerol Lipase Activity Decreases Glucose-Stimulated Insulin Secretion in INS-1 (832/13) Cells and Rat Islets

Lipid signals derived from lipolysis and membrane phospholipids play an important role in glucose-stimulated insulin secretion (GSIS), though the exact secondary signals remain unclear. Previous reports have documented a stimulatory role of exogenously added mono-acyl-glycerol (MAG) on insulin secre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Berdan, Charles A., Erion, Karel A., Burritt, Nathan E., Corkey, Barbara E., Deeney, Jude T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750965/
https://ncbi.nlm.nih.gov/pubmed/26867016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149008
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