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Mesoglycan attenuates VSMC proliferation through activation of AMP-activated protein kinase and mTOR

BACKGROUND: Vascular smooth muscle cells (VSMC) proliferation contributes significantly to intimal thickening in atherosclerosis and restenosis diseases. Platelet derived growth factor (PDGF) has been implicated in VSMC proliferation though the activation of multiple growth-promoting signals. Mesogl...

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Detalhes bibliográficos
Publicado no:Clin Hypertens
Main Authors: Lee, Kyung Young, Lee, Dong Hyup, Choi, Hyoung Chul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750809/
https://ncbi.nlm.nih.gov/pubmed/26893937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40885-016-0037-x
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