Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling

Aberrant fatty acid (FA) metabolism is a hallmark of proliferating cells, including untransformed fibroblasts or cancer cells. Lipolysis of intracellular triglyceride (TG) stores by adipose triglyceride lipase (ATGL) provides an important source of FAs serving as energy substrates, signaling molecul...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Cell Biol Lipids
Main Authors: Xie, Hao, Heier, Christoph, Kien, Benedikt, Vesely, Paul W., Tang, Zhiyuan, Sexl, Veronika, Schoiswohl, Gabriele, Strießnig-Bina, Isabelle, Hoefler, Gerald, Zechner, Rudolf, Schweiger, Martina
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397471/
https://ncbi.nlm.nih.gov/pubmed/32404277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2020.158737
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