Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling

Aberrant fatty acid (FA) metabolism is a hallmark of proliferating cells, including untransformed fibroblasts or cancer cells. Lipolysis of intracellular triglyceride (TG) stores by adipose triglyceride lipase (ATGL) provides an important source of FAs serving as energy substrates, signaling molecul...

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Detalles Bibliográficos
Publicado en:Biochim Biophys Acta Mol Cell Biol Lipids
Autores principales: Xie, Hao, Heier, Christoph, Kien, Benedikt, Vesely, Paul W., Tang, Zhiyuan, Sexl, Veronika, Schoiswohl, Gabriele, Strießnig-Bina, Isabelle, Hoefler, Gerald, Zechner, Rudolf, Schweiger, Martina
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397471/
https://ncbi.nlm.nih.gov/pubmed/32404277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2020.158737
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