The N-terminal Region of Comparative Gene Identification-58 (CGI-58) Is Important for Lipid Droplet Binding and Activation of Adipose Triglyceride Lipase

In mammals, excess energy is stored in the form of triacylglycerol primarily in lipid droplets of white adipose tissue. The first step of lipolysis (i.e. the mobilization of fat stores) is catalyzed by adipose triglyceride lipase (ATGL). The enzymatic activity of ATGL is strongly enhanced by CGI-58...

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Hlavní autoři: Gruber, Astrid, Cornaciu, Irina, Lass, Achim, Schweiger, Martina, Poeschl, Margret, Eder, Christina, Kumari, Manju, Schoiswohl, Gabriele, Wolinski, Heimo, Kohlwein, Sepp D., Zechner, Rudolf, Zimmermann, Robert, Oberer, Monika
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852968/
https://ncbi.nlm.nih.gov/pubmed/20164531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.064469
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