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Losartan Inhibits Vascular Smooth Muscle Cell Proliferation through Activation of AMP-Activated Protein Kinase

Losartan is a selective angiotensin II (Ang II) type 1 (AT(1)) receptor antagonist which inhibits vascular smooth muscle cells (VSMCs) contraction and proliferation. We hypothesized that losartan may prevent cell proliferation by activating AMP-activated protein kinase (AMPK) in VSMCs. VSMCs were tr...

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Bibliografski detalji
Glavni autori: Kim, Jung Eun, Choi, Hyoung Chul
Format: Artigo
Jezik:Inglês
Izdano: The Korean Physiological Society and The Korean Society of Pharmacology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997415/
https://ncbi.nlm.nih.gov/pubmed/21165328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2010.14.5.299
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