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Dengue Virus Activates the AMP Kinase-mTOR Axis To Stimulate a Proviral Lipophagy
Robust dengue virus (DENV) replication requires lipophagy, a selective autophagy that targets lipid droplets. The autophagic mobilization of lipids leads to increased β-oxidation in DENV-infected cells. The mechanism by which DENV induces lipophagy is unknown. Here, we show that infection with DENV...
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| Publicat a: | J Virol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5432877/ https://ncbi.nlm.nih.gov/pubmed/28298606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02020-16 |
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