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The Changing Role of mTOR Kinase in the Maintenance of Protein Synthesis during Human Cytomegalovirus Infection

The mammalian target of rapamycin (mTOR) kinase occurs in mTOR complex 1 (mTORC1) and complex 2 (mTORC2), primarily differing by the substrate specificity factors raptor (in mTORC1) and rictor (in mTORC2). Both complexes are activated during human cytomegalovirus (HCMV) infection. mTORC1 phosphoryla...

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Autori principali: Clippinger, Amy J., Maguire, Tobi G., Alwine, James C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126115/
https://ncbi.nlm.nih.gov/pubmed/21307192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01913-10
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